Adult Dominant Polycystic Kidney Disease is one of the most common autosomal dominant conditions in the world, affecting more than 600,000 Americans and 12.5 million persons worldwide-more than Down's syndrome, cystic fibrosis, sickle cell anemia and muscular dystrophy combined. One in 500 babies born have this disease.
ADPKD causes fluid filled sacs to grow on the kidney and overtake healthy kidney tissue. In 50 % of the cases, persons will develop kidney failure requiring dialysis and/or transplantation. At this time there is no specific treatment or cure. Parents affected have a 1 in 2 chance of passing it to each individual offspring. It does not skip a generation.
Symptoms can include high blood pressure, blood in the urine, abdominal discomfort,kidney stones, history of urinary tract infections and a family history of kidney failure. Medical intervention is important to treat such symptoms and to work to slow the progression of the kidney disease-if present-by preserving kidney function for as long as possible. ADPKD usually make excellent transplant candidates as they are often in otherwise very good health and the disease does not recur in the transplanted kidney.(ALTHO CYSTS IN THE LIVER CAN PERSIST THE RENAL ISSUES WILL NOT RECUR IN THE TRANSPLANTED KIDNEYS)
No comments:
Post a Comment